Introduction: On average, women spend one-third of their lives in menopause. This state is associated with several issues that could affect women's well-being. This study aims to determine the effect of cognitive behavior therapy in method group rates of anxiety and psychological resilience of menopausal women.

Methods: This study was performed based on a quasi-experimental study using pretest-posttest and control group design. The population of this study consists of all menopausal women referred to gynecology clinics in the city of Ramsar during the spring of 1394. In total, 32 women were selected according to inclusion and exclusion criteria and were randomly divided into two groups of 16 (treatment and control groups). Data was collected by “Beck's Anxiety Inventory” and “Connor- Davidson Resilience Scale” (CD-RISC). Face and content validity were confirmed by 7 experts and reliability of the questionnaires were confirmed using Cronbach’s Alpha. Experimental group was treated by cognitive behavior therapy in 8 sessions. Data was analyzed using SPSS/19.

Results: Cognitive behavior therapy in method group reduces anxiety (F = 152.029 and P < 0.01) and increases the psychological resilience (F = 106.688 and P < 0.01) in women in the experimental group. While in the control group, it had no significant effect.

Conclusions: It is assumed that, the cognitive behavior therapy in method group is a successful approach for decreasing anxiety and increasing psychological resilience in menopausal women. Therefore, it this approach is suggested for women in menopause state.