TY - JOUR T1 - The Effect of Resistance Training on Serum hs-CTnI and NT-proBNP Levels in Elderly Men TT - اثر تمرین مقاومتی بر سطوح سرمی تروپونین آی با حساسیت بالا و پپتید ناتریورتیک مغزی در مردان سالمند JF - jhpm.ir JO - jhpm.ir VL - 7 IS - 6 UR - http://jhpm.ir/article-1-961-en.html Y1 - 2019 SP - 17 EP - 24 KW - Resistance Exercise KW - Cardiac Troponin I KW - N-terminal pro-BNP KW - Elderly N2 - Introduction: Resistance exercises have beneficial effects on the health of the cardiovascular system and can be an effective treatment for a variety of clinical conditions, such as heart disease. The purpose of this study was to determine the effect of resistance training on serum hs-CTnI and NT-proBNP levels in elderly men. Methods: This study was a semi-experimental design with pretest-posttest design. 24 subjects were selected from among elderly men of Karaj (age: 72 ± 25.5, weight: 73.4 ± 13.3, BMI: 27.1 ± 4.1) as the subjects of this study and randomly divided into 2 groups of resistance training (12 subjects) and control (12 subjects). The protocol of resistance training was designed for eight weeks and three sessions per week with eight movements and each move with ten replications for the intervention group. The control group was in control of the Kahrizak sanatorium in order to compare it with the training group and to evaluate the effect of eight weeks of pre and post-test blood collection. To measure serum levels of NT-proBNP and hs-CTnI, the ELISA method and chemi luminescence were used respectively. The reliability of NT-proBNP and hs-CTnI kits were identified by identifiers (ZB-1239-H9648) and (ZB-11753S-H9648), respectively. Validity of the Kits used was determined by a survey of laboratory experts. Data was analyzed using SPSS. 24 software. Results: Serum levels of hs-CTnI and NT-proBNP showed a significant decrease after eight weeks of resistance training (P < 0.05). Also, the levels of NT-proBNP in the training group were significantly reduced after eight weeks of training compared to the control group (P < 0.05). Conclusions: Resistance exercises reduce the levels of prognostic biomarkers of heart disease hs-CTnI and NT-proBNP in older men. Therefore, providing resistance training programs can reduce the rate of atrophy of the skeletal and cardiac muscles and the phenomenon of sarcopenia, which occurs in old age, and maintain the levels of cardiac biomarkers in optimal conditions. M3 ER -