Introduction: Bed sore is an important nursing diagnosis in patients in ICU which delay recovery and increase costs of patients and their family. The best method for bed sores is dressing. The aim of the study was to compare the effect of honey dressing with hydrocolloid dressing on pressure ulcer healing in ICU patients.

 Materials and methods: In this randomized clinical trial research, 29 patients with total of 40 pressure ulcers were participated. After selecting the patient based on inclusion criteria, hospitals were divided randomly in two control and intervention groups. Intervention group with total of 20 pressure ulcers were received bed sore care with honey dressing in Shohada hospital and control group with total of 20 pressure ulcers were received bed sore care with hydrocolloid dressing in Farabi hospital. Ulcers state were measured with Pressure Ulcer Scale (PUSH) at the beginning of hospitalization and then weekly for 5 weeks. After intervention by comparing

PUSH score in two groups, recovery were measured. Data were analyzed by SPSS.

Findings: The results showed that the two groups were statistically similar with regard to baseline and wound characteristics.

After 5 weeks of treatment, patients who were treated by honey dressing had similar PUSH tool scores with patients that were treated with hydrocolloid dressing. However, recovery in group with honey dressing was faster, but there was not any significant difference.

Conclusion: Results showed that healing among patients that were treated with honey dressing were statistically similar with the comparison group. But easy accessibility, economical and neutrality makes honey dressing treatment as choice for pressure ulcers treatment.