Introduction: Earthquake is one type of natural disasters which results in massive physical, economical and life losses. As it is an unexpected phenomena, it is necessary to plan for mitigation and preparedness of the cause. This research was aimed at assessing the vulnerability of general hospitals of Tehran University of Medical Sciences at time of earthquake.

Materials and Methods: In this descriptive study, disaster risk in all 6 general hospitals at Tehran University of Medical Sciences were examined in three dimensions of structural, nonstructural and managerial with informant personnel. Data were collected by the "Hospital Disaster Risk Assessment" instrument developed by "World Health Organization". The face and content validity and reliability of this instrument have been confirmed in similar studies. The result was analyzed using Microsoft Office Excel 2007 software.

Findings: Structural vulnerability of all 6 hospitals was at intermediate safety level with a minimum of 12 and maximum of 18 points. Considering nonstructural vulnerability  4 hospitals had high safety level and 2 hospitals had intermediate level. Findings of managerial vulnerability assessment indicate that 5 hospitals had high safety level and 1 hospital was in low level. The minimum and maximum scores of this section were 48 and 99.

Conclusion:   Majority of hospitals were in the intermediate level of safety, In the event of an earthquake with moderate intensity the residents of the hospitals might be safe from damages, but they will not be able to provide uninterrupted services. To improve safety levels of hospitals, re-locating different sections of hospitals is recommended.